The following adverse reactions have been reported coincident with the administration of methocarbamol. Some events may have been due to an overly rapid rate of intravenous injection.
Body as a whole: Anaphylactic reaction, angioneurotic edema, fever, headache
Cardiovascular system: Bradycardia, flushing, hypotension, syncope, thrombophlebitis
In most cases of syncope there was spontaneous recovery. In others, epinephrine, injectable steroids, and/or injectable antihistamines were employed to hasten recovery.
Digestive system: Dyspepsia, jaundice (including cholestatic jaundice), nausea and vomiting
Hemic and lymphatic system: Leukopenia
Immune system: Hypersensitivity reactions
Nervous system: Amnesia, confusion, diplopia, dizziness or light-headedness, drowsiness, insomnia, mild muscular incoordination, nystagmus, sedation, seizures (including grand mal), vertigo
The onset of convulsive seizures during intravenous administration of methocarbamol has been reported in patients with seizure disorders. The psychic trauma of the procedure may have been a contributing factor. Although several observers have reported success in terminating epileptiform seizures with ROBAXIN Injectable, its administration to patients with epilepsy is not recommended (see PRECAUTIONS, General).
Skin and special senses: Blurred vision, conjunctivitis, nasal congestion, metallic taste, pruritus, rash, urticaria
Other: Pain and sloughing at the site of injection
Robaxin Side Effects
For the Consumer
Side effects requiring immediate medical attention
Along with its needed effects, methocarbamol (the active ingredient contained in Robaxin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking methocarbamol:
Incidence not known
- Black, tarry stools
- changes in skin color
- chest pain or discomfort
- clay-colored stools
- dark urine
- difficulty in swallowing
- fast heartbeat
- feeling of warmth
- joint or muscle pain
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- lightheadedness, dizziness, or fainting
- loss of appetite
- loss of bladder control
- loss or problems with memory
- numbness or tingling of face, hands, or feet
- pain, tenderness, or swelling of foot or leg
- painful or difficult urination
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- redness and soreness of the eyes
- redness of the face, neck, arms, and occasionally, upper chest
- skin rash
- slow or irregular heartbeat
- sore throat
- sores, ulcers, or white spots on the lips or in the mouth
- stomach pain
- swollen glands
- tightness in the chest
- total body jerking
- unpleasant breath odor
- unusual bleeding or bruising
- unusual tiredness or weakness
- vomiting of blood
- yellow eyes or skin
Get emergency help immediately if any of the following symptoms of overdose occur while taking methocarbamol:
Symptoms of Overdose
- Loss of consciousness
- shaking or jerking of one area or side of the body
Side effects not requiring immediate medical attention
Some side effects of methocarbamol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- double vision
- feeling of constant movement of self or surroundings
- mood or mental changes
- sensation of spinning
- stomach discomfort, upset, or pain
- trouble sleeping
- uncontrolled eye movements
Adverse reactions reported coincident with the administration of methocarbamol include
Body as a whole: Angioneurotic oedema, anaphylactic reaction, fever, headache.
Cardiovascular system: Bradycardia, flushing, hypotension, syncope.
Digestive system: Dyspepsia, jaundice (including cholestatic jaundice), nausea and vomiting.
Blood and lymphatic system: Leucopenia.
Nervous system: Restlessness, anxiety, tremor, amnesia, confusion, diplopia, dizziness or light-headedness, vertigo, drowsiness, insomnia, mild muscular incoordination, nystagmus, seizures (including grand mal).
Skin and special senses: Blurred vision, conjunctivitis with nasal congestion, metallic taste, pruritus, rash, urticaria.
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard.